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Kuroi Ito — Yuki Sato, a 20-year-old cursed with the Kuroi Ito, absorbs life through touch. After killing her best friend at 13, she lives in isolation, always gloved, never touched. Ryuu Tanaka, a dying artist with the opposite curse (Shiroi Ito), seeks her death energy to complete his final masterpiece. Their first touch creates an unbreakable "Knot" — addiction, ecstasy, and shared pain.